Synthace

Synthace is a pioneering R&D cloud platform specifically designed for life sciences, aiming to revolutionize the way biological research and drug discovery are conducted. It addresses the critical challenge of slow, complex, and often manual experimentation processes that create bottlenecks in the development pipeline. By integrating powerful software with the hands-on expertise of its Field Application Scientists, Synthace provides a comprehensive solution that empowers research teams to achieve faster, more definitive results.

The platform is built around the principle of multifactorial experimentation, such as Design of Experiments (DoE), which allows scientists to test numerous variables simultaneously. This is a significant leap from traditional one-factor-at-a-time (OFAT) methods, enabling a much deeper understanding of complex biological systems in a fraction of the time. Synthace makes these advanced methodologies accessible and practical for everyday lab work, bridging the gap between experimental design, robotic execution, and data analysis.

How to use Synthace

Synthace's implementation is a collaborative partnership rather than a simple software installation. The process is structured to ensure success and organizational adoption:

1. Consultation & Project Identification: The engagement begins with Synthace's specialists working closely with your team to understand your scientific goals and challenges. Together, they identify initial high-impact projects where the platform can deliver immediate value.
2. Multifactorial Experimental Design: Using the intuitive, visual interface of the Synthace software, scientists can design complex DoE studies without needing to be statistics experts. The platform guides the creation of experiments that efficiently explore a vast design space.
3. Automated Execution: The software translates the complex experimental design into simple, executable protocols for your existing lab automation hardware, such as liquid handlers and dispensers. It automates all the complex calculations for dilutions, transfers, and plate layouts, minimizing the risk of human error.
4. Structured Data Capture & Analysis: As the experiment runs, Synthace automatically captures and structures all the relevant data and metadata. This creates a complete, analysis-ready dataset, linking results directly back to the experimental conditions, which dramatically simplifies and accelerates the analysis phase.
5. Scaling & Empowerment: Following the success of initial projects, Synthace provides comprehensive training and support to help your organization scale the methodology. The goal is to make your teams self-sufficient in using this powerful approach to accelerate all future R&D programs.

Core Features of Synthace

• No-Code Experimental Design & Automation: A visual, drag-and-drop interface allows scientists to design and automate complex biological workflows without writing any code.
• Design of Experiments (DoE) Integration: Natively supports multifactorial experimental designs, enabling comprehensive system characterization and optimization.
• Lab Hardware Integration: Offers seamless integration with a wide range of common laboratory liquid handlers, dispensers, and analytical instruments, creating a connected lab ecosystem.
• Automated Data Structuring: Automatically collects, contextualizes, and structures experimental data, creating a 'digital twin' of the experiment for robust analysis and improved data integrity.
• Dedicated Expert Support: Access to a team of Field Application Scientists who provide deep domain expertise in biology, automation, and data science to ensure customer success.

Use Cases for Synthace

Synthace is versatile and can be applied across various stages of biopharmaceutical R&D:

• Assay Development & Optimization: Rapidly develop and optimize robust biochemical and cellular assays by systematically exploring variables like reagent concentrations, incubation times, and cell densities.
• Protein & Antibody Engineering: Streamline the design, construction, and testing of large libraries of genetic constructs or protein variants to identify candidates with desired properties.
• Cell Line Development: Efficiently optimize cell culture conditions, media formulations, and production processes to improve yield and product quality.
• Drug Discovery & Lead Optimization: Accelerate the screening and characterization of lead compounds, enabling faster and more confident go/no-go decisions.
• Synthetic Biology: Apply machine learning and multifactorial methods to design, build, and test complex gene circuits and metabolic pathways.

Advantages of Synthace

The platform offers significant competitive advantages:

• Accelerated R&D Timelines: Customers report taking months off their drug discovery timelines, leading to faster progress through the pipeline.
• Massively Increased Throughput: Enables teams to conduct far more complex and comprehensive experiments, with some users reporting a more than tenfold increase in experimental throughput.
• Deeper Scientific Insight: Moves beyond simple pass/fail results to provide a rich, multidimensional understanding of biological systems.
• Enhanced Reproducibility and Reliability: Automation and standardized data capture minimize human error, leading to highly reproducible and trustworthy data.
• Empowers Scientists: Automates tedious and error-prone manual tasks, freeing up valuable scientist time to focus on strategic thinking, data interpretation, and innovation.

Pricing and Plans

Synthace operates on a customized enterprise pricing model. The solution includes software licensing, dedicated support from Field Application Scientists, and implementation services tailored to the specific needs and scale of the client's organization. Due to the bespoke nature of the offering, pricing is not publicly listed. Interested organizations are encouraged to request a demo through the Synthace website to receive a detailed consultation and a custom quote.